Neuroscience
106 Results
Pharmacologic reversal of advanced Alzheimer’s disease in mice and identification of potential therapeutic nodes in human brain
The stroke risk gene Foxf2 maintains brain endothelial cell function via Tie2 signaling
Bioenergetic and protein processing imbalances in iPSC-dopamine neurons from individuals with idiopathic Parkinson’s disease
Reversal of auditory cortical hyperexcitability and restoration of synaptic plasticity balance by GluN1-mediated photobiomodulation in noise-induced tinnitus
Deep learning for brain electron microscopy segmentation: Advances, challenges, and future directions in connectomics and ultrastructure analysis
Characterization of astrocytic primary cilia in the adult mouse cortex and hippocampus
Transcriptional dynamics of the oligodendrocyte lineage and its regulation by the brain erythropoietin system
VTA monosynaptic connections by local glutamate and GABA neurons and their distinct roles in behavior
The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex
Scientists Map Miles of Wiring in a Speck of Mouse Brain – The New York Times
Functional connectomics spanning multiple areas of mouse visual cortex
Inhibitory specificity from a connectomic census of mouse visual cortex
Quantifying axonal features of human superficial white matter from three-dimensional multibeam serial electron microscopy data assisted by deep learning
Comparative prospects of imaging methods for whole-brain mammalian connectomics
Volume electron microscopy reveals 3D synaptic nanoarchitecture in postmortem human prefrontal cortex
Volume electron microscopy reveals 3D synaptic nanoarchitecture in postmortem human prefrontal cortex
Valproic acid ameliorates morpho-dysfunctional effects triggered by Ischiatic nerve crush injury-induced by compression model in mice: Nerve regeneration and immune-modulatory pathway
Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding b-amyloidosis
Nrf-2 modulates excitability of hippocampal neurons by regulating ferroptosis and neuroinflammation after subarachnoid hemorrhage in rats
Acutely blocking excessive mitochondrial fission prevents chronic neurodegeneration after traumatic brain injury
Volume electron microscopy for genetically and molecularly defined neural circuits
Remyelination by surviving oligodendrocytes is inefficient in the inflamed mammalian cortex
Multiplexed volumetric CLEM enabled by scFvs provides insights into the cytology of cerebellar cortex
RoboEM: automated 3D flight tracing for synaptic-resolution connectomics
Comparative connectomics of dauer reveals developmental plasticity
Fast imaging of millimeter-scale areas with beam deflection transmission electron microscopy
Stretch triggers microtubule stabilization and MARCKS-dependent membrane incorporation in the shaft of embryonic axons
vEM reveals the cellular composition of the Blood Nerve Barrier
Distinct molecular profiles of skull bone marrow in health and neurological disorders
Remyelination by surviving oligodendrocytes is inefficient in the inflamed mammalian cortex
Parallel neurodegenerative phenotypes in sporadic Parkinson’s disease fibroblasts and midbrain dopamine neurons
It takes two to remyelinate: A bioengineered platform to study astrocyte-oligodendrocyte crosstalk and potential therapeutic targets in remyelination
High-contrast en bloc staining of mouse whole-brain and human brain samples for EM-based connectomics
Developmental exposure to domoic acid targets reticulospinal neurons and leads to aberrant myelination in the spinal cord
Spatial Transcriptomics-correlated Electron Microscopy maps transcriptional and ultrastructural responses to brain injury
Finding Needles in a Haystack with Light: Resolving the Microcircuitry of the Brain with Fluorescence Microscopy
Reconstructing neural circuits using multiresolution correlated light and electron microscopy
Proteomic screen reveals diverse protein transport between connected neurons in the visual system
Plasticity of cell proliferation in the retina of Austrolebias charrua fish under light and darkness conditions
A versatile viral toolkit for functional discovery in the nervous system
Alterations in biogenic amines levels associated with age-related muscular tissue impairment in Drosophila melanogaster
Multi-scale light microscopy/electron microscopy neuronal imaging from brain to synapse with a tissue clearing method, ScaleSF
Deep residual contextual and subpixel convolution network for automated neuronal structure segmentation in micro-connectomics
Fear memory-associated synaptic and mitochondrial changes revealed by deep learning-based processing of electron microscopy data
Reconstruction of ovine axonal cytoarchitecture enables more accurate models of brain biomechanics
Oligodendroglial macroautophagy is essential for myelin sheath turnover to prevent neurodegeneration and death
A connectomic study of a petascale fragment of human cerebral cortex
Connectomes across development reveal principles of brain maturation
Rapid Ultrastructural Changes in the PSD and Surrounding Membrane after Induction of Structural LTP in Single Dendritic Spines
Δ9-Tetrahydrocannabinol promotes functional remyelination in the mouse brain
Reconstruction of motor control circuits in adult Drosophila using automated transmission electron microscopy
Primate neuronal connections are sparse in cortex as compared to mouse
Multi-modal imaging of a single mouse brain over five orders of magnitude of resolution
Neuronal delivery of nanoparticles via nerve fibres in the skin
ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism
ATUM-FIB microscopy for targeting and multiscale imaging of rare events in mouse cortex
Myelin replacement triggered by single-cell demyelination in mouse cortex
Correlative Ultrastructural Analysis of Functionally Modulated Synapses Using Automated Tape-Collecting Ultramicrotome and SEM Array Tomography Correlative Ultrastructural Analysis of Functionally Modulated Synapses Using Automated Tape-Collecting Ultramicrotome and SEM Array Tomography
Long-Range Optogenetic Control of Axon GuidanceOvercomes Developmental Boundaries and Defects
A petascale automated imaging pipeline for mapping neuronal circuits with high-throughput transmission electron microscopy
Myelin replacement triggered by single-cell demyelination in mouse cortex
An Individual Interneuron Participates in Many Kinds of Inhibition and Innervates Much of the Mouse Visual Thalamus
Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation
Pathology of myelinated axons in the PLP-deficient mouse model of spastic paraplegia type 2 revealed by volume imaging using focused ion beam-scanning electron microscopy
Sensory Experience Engages Microglia to Shape Neural Connectivity through a Non-Phagocytic Mechanism
Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease
Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease
Developmental Rewiring between Cerebellar Climbing Fibers and Purkinje Cells Begins with Positive Feedback Synapse Addition
Presynaptic Mitochondria Volume and Abundance Increase during Development of a High-Fidelity Synapse
The Retinal Ganglion Cell Transportome Identifies Proteins Transported to Axons and Presynaptic Compartments in the Visual System In Vivo
A subacute model of glaucoma based on limbal plexus cautery in pigmented rats
Decreased dopamine in striatum and difficult locomotor recovery from MPTP insult after exposure to radiofrequency electromagnetic fields
UNI-EM: An Environment for Deep Neural Network-Based Automated Segmentation of Neuronal Electron Microscopic Images
Quantitative synchrotron X-ray tomography of the material-tissue interface in rat cortex implanted with neural probes
Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS
Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition
Evaluating seasonal changes of cone photoreceptor structure in the 13-lined ground squirrel
Plasticity of Unmyelinated Fibers in a Side-to-end Tubulization Model
A Complete Electron Microscopy Volume of the Brain of Adult Drosophila melanogaster
Large Volume Electron Microscopy and Neural Microcircuit Analysis
Correlated Light-Serial Scanning Electron Microscopy (CoLSSEM) for ultrastructural visualization of single neurons in vivo
Flexible Learning-Free Segmentation and Reconstruction of Neural Volumes
A micro-CT-based method for quantitative brain lesion characterization and electrode localization
Progress and remaining challenges in high-throughput volume electron microscopy
A carbon nanotube tape for serial-section electron microscopy of brain ultrastructure
Whole-brain serial-section electron microscopy in larval zebrafish
Electron Microscopic Reconstruction of Functionally Identified Cells in a Neural Integrator
Cos2/Kif7 and Osm-3/Kif17 regulate onset of outer segment development in zebrafish photoreceptors through distinct mechanisms
Stable Positioning of Unc13 Restricts Synaptic Vesicle Fusion to Defined Release Sites to Promote Synchronous Neurotransmission
Reconstruction of genetically identified neurons imaged by serial-section electron microscopy
High-Throughput, High-Resolution Mapping of Protein Localization in Mammalian Brain by In Vivo Genome Editing
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