Skip to main content

Biomedical Science

132 Results

Honokiol modulates invasion and autophagy in pancreatic cancer via the miR-101/QKI axis in cancer-associated fibroblasts


Are all nanoplastics equally neurotoxic? Influence of size and surface functionalization on the toxicity of polystyrene nanoplastics in human neuronal cells


Propolis-loaded liposomes (ProLip) enhance macrophage-mediated immunomodulation and suppress breast cancer cell proliferation


Rac1 inhibition prevents axonal cytoskeleton dysfunction in transthyretin amyloid polyneuropathy


Mitochondrial-encoded peptide MOTS-c prevents pancreatic islet cell senescence to delay diabetes


Exo-miR-1911-5p regulates ferroptosis to promote macrophages M2 polarization-mediated gastric cancer cisplatin resistance via MYB/AKR1B10/ACC


Integrative transcriptogenomic analyses reveal the regulatory network underlying rice eating and cooking quality and identify a role for alpha-globulin in modulating starch and sucrose metabolism


Mitochondrial RNA/RIG-I promotes Caspase-1/GSDMD-mediated inflammation in sepsis-associated acute kidney injury


Impact of antibiotics on membrane vesicle production in GroupB Streptococcus


New insight into teratogenic effects of (S)-thalidomide in zebrafish embryos growing inside the chorion and subjected to electric pulses


Establishment of a 3D multi-layered in vitro model of inflammatory bowel disease


New insights into persistent corneal subepithelial infiltrates following epidemic keratoconjunctivitis: The first case report with ultrastructural and immunohistochemical investigations


Advancing osteosarcoma 3D modeling in vitro for novel tumor microenvironment-targeted therapies development


Establishment of a 3D multi-layered in vitro model of inflammatory bowel disease


Histone H1 kills MRSA


Effects of silver-decorated PLGA nanoparticles on Staphylococcus epidermidis biofilms and evaluation of the detoxification limit of bacteria against these nanoparticles


A study on the hepatic response to heat stress in Gymnocypris eckloni through an approach combining metabolomic and transcriptomic profiling


Cardiolipin oxidized by ROS from Complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia


Excessive free fatty acid sensing in pituitary lactotrophs elicits steatotic liver disease by decreasing prolactin levels


Cyclohexylalanine-Containing α‑Helical Amphipathic Peptide Targets Cardiolipin, Rescuing Mitochondrial Dysfunction in Kidney Injury


Antimicrobial activity of a natural compound and analogsagainst multi-drug-resistant Gram-positive pathogens


Ultrastructural, metabolic and genetic characteristics of determinants facilitating the acquisition of macrolide resistance by Streptococcus pneumoniae


Peroxiredoxin 4 deficiency induces accelerated ovarian aging through destroyed proteostasis in granulosa cells


Antibody-ligand interactions on a high-capacity staphylococcal protein A resin


Antibody-ligand interactions on a high-capacity staphylococcal protein A resin


Putative effect of chronic renal failure on granular convoluted tubule of submandibular gland in male rats: Immunohistochemical and ultrastructural study


More than the barrier effect: Biodegradable Mg-Ag alloy membranes for guided bone/tissue regeneration


A robust transformer-based pipeline of 3D cell alignment denoise and instance segmentation on electron microscopy sequence images


Effect of exogenous calcitriol on myopia development and axial length in guinea pigs with form deprivation myopia


Preclinical evaluation of polymer encapsulated carbon-based nano and microparticles for sentinel lymph node tattooing


PIEZO acts in an intestinal valve to regulate swallowing in C. elegans


Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver


Three-dimensional correlative microscopy of the Drosophila female reproductive tract reveals modes of communication in seminal receptacle sperm storage


Autophagy modulation attenuates sorafenib resistance in HCC induced in rats


Laterality, sexual dimorphism, and human vagal projectome heterogeneity shape neuromodulation to vagus nerve stimulation


Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization


Nonvesicular lipid transfer drives myelin growth in the central nervous system


Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration


Fuzhuan brick tea extract ameliorates obesity-induced skeletal muscle atrophy by alleviating mitochondrial dysfunction in mice


Multimodal study of CHI3L1 inhibition and its effect on angiogenesis, migration, immune response and refractive index of cellular structures in glioblastoma


Adolescent exposure to low-dose THC disrupts energy balance and adipose organ homeostasis in adulthood


Development and preclinical evaluation of bioactive nerve conduits for peripheral nerve regeneration: A comparative study


Visualization of basement membranes by a nidogen-based fluorescent reporter in mice


Combination of cobalt, chromium and titanium nanoparticles increases cytotoxicity in vitro and pro-inflammatory cytokines in vivo


Reprogramming of tumor-associated macrophages by polyaniline-coated iron oxide nanoparticles applied to treatment of breast cancer


Cancer/testis antigen CAGE mediates osimertinib resistance in non-small cell lung cancer cells and predicts poor prognosis in patients with pulmonary adenocarcinoma


Enhanced peripheral nerve regeneration by mechano-electrical stimulation


Bacteroides Fragilis in the gut microbiomes of Alzheimer’s disease activates microglia and triggers pathogenesis in neuronal C/EBPβ transgenic mice


Intestinal epithelial barrier integrity investigated by label-free techniques in ulcerative colitis patients


SYPL1 defines a vesicular pathway essential for sperm cytoplasmic droplet formation and male fertility


m6A demethylase ALKBH5 attenuates doxorubicin-induced cardiotoxicity via posttranscriptional stabilization of Rasal3


Rosiglitazone Reverses Inflammation in Epididymal White Adipose Tissue in Hormone-Sensitive Lipase-Knockout Mice


Heterotypic cell-in-cell structures between cancer and NK cells are associated with enhanced anticancer drug resistance


Histopathological, ultrastructural, and biochemical traits of apoptosis induced by peroxisomicine A1 (toxin T-514) from Karwinskia parvifolia in kidney and lung


Vitamin B3, nicotinamide, enhances mitochondrial metabolism to promote differentiation of the retinal pigment epithelium


Ibuprofen and diclofenac differentially affect cell viability, apoptosis and morphology changes of human cholangiocarcinoma cell lines


Intravitreal Administration of Stanniocalcin-1 Rescues Photoreceptor Degeneration with Reduced Oxidative Stress and Inflammation in a Porcine Model of Retinitis Pigmentosa


In-silico predicting as a tool to develop plant-based biomedicines and nanoparticles: Lycium shawii metabolites


Fibroblasts repair blood-brain barrier damage and hemorrhagic brain injury via TIMP2


Visceral fat inflammation and fat embolism are associated with lung’s lipidic hyaline membranes in subjects with COVID-19


Attenuation of ischemia–reperfusion injury by intracoronary chelating agent administration


Early macrophage response to obesity encompasses Interferon Regulatory Factor 5 regulated mitochondrial architecture remodelling


Tissue extracellular matrix hydrogels as alternatives to Matrigel for culturing gastrointestinal organoids


Prostaglandin-based rAAV-mediated glaucoma gene therapy in Brown Norway rats


MC5R Contributes to Sensitivity to UVB Waves and Barrier Function in Mouse Epidermis


Silver Nanoparticles Formation by Jatropha integerrima and LC/MS-QTOF-Based Metabolite Profiling


Targeted delivery of a phosphoinositide 3-kinase γ inhibitor to restore organ function in sepsis


Recruitment and remodeling of peridroplet mitochondria in human adipose tissue


Noradrenergic fibers are associated with beta-cell dedifferentiation and impaired beta-cell function in humans


Peripheral IL-6/STAT3 signaling promotes beiging of white fat


Large-scale 3D imaging of mouse cochlea using serial block-face scanning electron microscopy


Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells


Atomic force microscopy analysis of native infectious and inactivated SARS-CoV-2 virions


An App knock-in rat model for Alzheimer’s disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments


Self-assembling human heart organoids for the modeling of cardiac development and congenital heart disease


Astrocytic atrophy as a pathological feature of Parkinson’s disease with LRRK2 mutation


Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes


Human organ donor-derived vagus nerve biopsies allow for well-preserved ultrastructure and high-resolution mapping of myelinated and unmyelinated fibers


Emerging electron microscopy and 3D methodologies to interrogate Staphylococcus aureus osteomyelitis in murine models


Microneedles with dual release pattern for improved immunological efficacy of Hepatitis B vaccine


Clofibrate improves myocardial ischemia-induced damage through regulation of renin-angiotensin system and favours a pro-vasodilator profile in left ventricle


Analysis of the three dimensional structure of the kidney glomerulus capillary network


MSCs ameliorate hepatocellular apoptosis mediated by PINK1-dependent mitophagy in liver ischemia/reperfusion injury through AMPKα activation


Selective effects of protein 4.1N deficiency on neuroendocrine and reproductive systems


Reorganization of perineuronal nets in the medial Preoptic Area during the reproductive cycle in female rats


Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis


CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves


Virus Isolation from the First Patient with SARS-CoV-2 in Korea


Amelogenin phosphorylation regulates tooth enamel formation by stabilizing a transient amorphous mineral precursor


Effect of Unloading Condition on the Healing Process and Effectiveness of Platelet Rich Plasma as a Countermeasure: Study on In Vivo and In Vitro Wound Healing Models


New bioresorbable wraps based on oxidized polyvinyl alcohol and leukocyte-fibrin-platelet membrane to support peripheral nerve neurorrhaphy_ preclinical comparison versus NeuraWrap


Dynamic Regulation of Caveolin-1 Phosphorylation and Caveolae Formation by Mammalian Target of Rapamycin Complex 2 in Bladder Cancer Cells


Chemical composition and protective effect of Juniperus sabina L. essential oil against CCl4 induced hepatotoxicity


Early exposure to radiofrequency electromagnetic fields at 1850 MHz affects auditory circuits in early postnatal mice


Versican is crucial for the initiation of cardiovascular lumen development in medaka (Oryzias latipes)


Mouse pancreatic ductal organoid culture as a relevant model to study exocrine pancreatic ion secretion


Evaluation of the Structure of Myodural Bridges in an Equine Model of Ehlers-Danlos Syndromes


GLP-1 receptor agonist liraglutide has a neuroprotective effect on an aged rat model of Wolfram syndrome


Chlamydia trachomatis CT229 Subverts Rab GTPase-Dependent CCV Trafficking Pathways to Promote Chlamydial Infection


Data on SD-OCT image acquisition, ultrastructural features, and horizontal tissue shrinkage in the porcine retina