Author: Nick Zhuang

Protocol for preparation of heterogeneous biological samples for 3D electron microscopy: a case study for insects

Written by Nick Zhuang on 2021. Posted in ATUMtome, Environmental Science and Sustainability.

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An App knock-in rat model for Alzheimer’s disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments

Written by Nick Zhuang on 2021. Posted in ATUMtome, Biomedical Science.

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The molecular dynamics of subdistal appendages in multi-ciliated cells

Written by Nick Zhuang on 2021. Posted in Cell Biology, MTX.

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Self-assembling human heart organoids for the modeling of cardiac development and congenital heart disease

Written by Nick Zhuang on 2021. Posted in Biomedical Science, PowerTome.

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Identification of efficient prokaryotic cell-penetrating peptides with applications in bacterial biotechnology

Written by Nick Zhuang on 2021. Posted in Cell Biology, MTXL.

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Astrocytic atrophy as a pathological feature of Parkinson’s disease with LRRK2 mutation

Written by Nick Zhuang on 2021. Posted in Biomedical Science, PowerTome.

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Tetraploid Citrumelo 4475 rootstocks improve diploid common clementine tolerance to long-term nutrient deficiency

Written by Nick Zhuang on 2021. Posted in Plant Science, PowerTome.

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Self-ordered nanospike porous alumina fabricated under a new regime by an anodizing process in alkaline media

Written by Nick Zhuang on 2021. Posted in Advanced Materials, Nanotechnology and Advanced Materials, PowerTome.

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Residual polymer stabiliser causes anisotropic electrical conductivity during inkjet printing of metal nanoparticles

Written by Nick Zhuang on 2021. Posted in Nanotechnology and Advanced Materials, Plastics and Polymers, PowerTome.

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The cell envelope of Staphylococcus aureus selectively controls the sorting of virulence factors

Written by Nick Zhuang on 2021. Posted in Cell Biology, CRX, PowerTome.

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Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes

Written by Nick Zhuang on 2021. Posted in Biomedical Science, PowerTome.

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Neuronal delivery of nanoparticles via nerve fibres in the skin

Written by Nick Zhuang on 2021. Posted in Neuroscience, PowerTome.

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A shape-adjusted ellipse approach corrects for varied axonal dispersion angles and myelination in primate nerve roots

Written by Nick Zhuang on 2021. Posted in Cell Biology, PowerTome.

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Mitochondrial movement during its association with chloroplasts in Arabidopsis thaliana

Written by Nick Zhuang on 2021. Posted in Cell Biology, PowerTome.

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Human organ donor-derived vagus nerve biopsies allow for well-preserved ultrastructure and high-resolution mapping of myelinated and unmyelinated fibers

Written by Nick Zhuang on 2021. Posted in Biomedical Science, PowerTome.

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Evidence of a new hidden neural network into deep fasciae

Written by Nick Zhuang on 2021. Posted in Neuroscience, PowerTome.

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On the limitations in assessing stability of oxygen evolution catalysts using aqueous model electrochemical cells

Written by Nick Zhuang on 2021. Posted in Advanced Materials, PowerTome.

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Analysis of the three dimensional structure of the kidney glomerulus capillary network

Written by Nick Zhuang on 2020. Posted in ATUMtome, Biomedical Science.

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Myelin replacement triggered by single-cell demyelination in mouse cortex

Written by Nick Zhuang on 2020. Posted in ATUMtome, Neuroscience.

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MSCs ameliorate hepatocellular apoptosis mediated by PINK1-dependent mitophagy in liver ischemia/reperfusion injury through AMPKα activation

Written by Nick Zhuang on 2020. Posted in Biomedical Science, MT6000.

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Antimicrobial and antibiofilm activities of ursolic acid against carbapenem-resistant Klebsiella pneumoniae

Written by Nick Zhuang on 2020. Posted in Cell Biology, MTX.

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Maize GOLDEN2-LIKE genes enhance biomass and grain yields in rice by improving photosynthesis and reducing photoinhibition

Written by Nick Zhuang on 2020. Posted in Plant Science, PowerTome.

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PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming

Written by Nick Zhuang on 2020. Posted in Cell Biology, MTX.

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Multicellular contractility contributes to the emergence of mesothelioma nodules

Written by Nick Zhuang on 2020. Posted in Cell Biology, MT7000.

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Structural variability of dyads relates to calcium release in rat ventricular myocytes

Written by Nick Zhuang on 2020. Posted in Cell Biology, MTXL.

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Selective effects of protein 4.1N deficiency on neuroendocrine and reproductive systems

Written by Nick Zhuang on 2020. Posted in Biomedical Science, MTXL.

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Nanoscopic X-ray tomography for correlative microscopy of a small meiofaunal sea-cucumber

Written by Nick Zhuang on 2020. Posted in Environmental Science and Sustainability, MTXL.

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Gene products and processes contributing to lanthanide homeostasis and methanol metabolism in Methylorubrum extorquens AM1

Written by Nick Zhuang on 2020. Posted in Cell Biology, PowerTome.

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Morphology, ultrastructure, genomics, and phylogeny of Euplotes vanleeuwenhoeki sp. nov. and its ultra-reduced endosymbiont “Candidatus Pinguicoccus supinus” sp. nov.

Written by Nick Zhuang on 2020. Posted in Environmental Science and Sustainability, PowerTome.

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Mechanisms of action of antimicrobial peptides ToAP2 and NDBP-5.7 against Candida albicans planktonic and biofilm cells

Written by Nick Zhuang on 2020. Posted in Cell Biology, PowerTome.

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β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis

Written by Nick Zhuang on 2020. Posted in Cell Biology, PowerTome.

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An iron (II) dependent oxygenase performs the last missing step of plant lysine catabolism

Written by Nick Zhuang on 2020. Posted in MR2, Plant Science.

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In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy

Written by Nick Zhuang on 2020. Posted in Cell Biology, PowerTome.

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Reorganization of perineuronal nets in the medial Preoptic Area during the reproductive cycle in female rats

Written by Nick Zhuang on 2020. Posted in Biomedical Science, PowerTome.

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Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis

Written by Nick Zhuang on 2020. Posted in Biomedical Science, PowerTome.

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A petascale automated imaging pipeline for mapping neuronal circuits with high-throughput transmission electron microscopy

Written by Nick Zhuang on 2020. Posted in ATUMtome, Neuroscience.

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CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves

Written by Nick Zhuang on 2020. Posted in Biomedical Science, PowerTome.

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Hierarchically-structured metalloprotein composite coatings biofabricated from co-existing condensed liquid phases

Written by Nick Zhuang on 2020. Posted in Advanced Materials, PowerTome.

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Myelin replacement triggered by single-cell demyelination in mouse cortex

Written by Nick Zhuang on 2020. Posted in ATUMtome, Neuroscience.

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Ultra-black Camouflage in Deep-Sea Fishes

Written by Nick Zhuang on 2020. Posted in Environmental Science and Sustainability, MT6000.

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Sensory Experience Engages Microglia to Shape Neural Connectivity through a Non-Phagocytic Mechanism

Written by Nick Zhuang on 2020. Posted in ATUMtome, Neuroscience.

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Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease

Written by Nick Zhuang on 2020. Posted in Neuroscience, PowerTome.

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Microscopy Techniques for NEUROSCIENCE

Written by Nick Zhuang on 2019. Posted in ATUMtome, Neuroscience.

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Adipocyte lipolysis affects Perilipin 5 and cristae organization at the cardiac lipid droplet-mitochondrial interface

Written by Nick Zhuang on 2019. Posted in Cell Biology, MR2.

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Antifungal activity and mechanism of action of Ou-gon (Scutellaria root extract) components against pathogenic fungi

Written by Nick Zhuang on 2019. Posted in MT7000, Plant Science.

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Early exposure to radiofrequency electromagnetic fields at 1850 MHz affects auditory circuits in early postnatal mice

Written by Nick Zhuang on 2019. Posted in Biomedical Science, MTX.

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Versican is crucial for the initiation of cardiovascular lumen development in medaka (Oryzias latipes)

Written by Nick Zhuang on 2019. Posted in Biomedical Science, MT6000.

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A subacute model of glaucoma based on limbal plexus cautery in pigmented rats

Written by Nick Zhuang on 2019. Posted in Neuroscience, PowerTome.

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Decreased dopamine in striatum and difficult locomotor recovery from MPTP insult after exposure to radiofrequency electromagnetic fields

Written by Nick Zhuang on 2019. Posted in MTX, Neuroscience.

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The NuRD chromatin-remodeling complex enzyme CHD4 prevents hypoxia-induced endothelial Ripk3 transcription and murine embryonic vascular rupture

Written by Nick Zhuang on 2019. Posted in Cell Biology, MT7000.

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Collagen fibrils and proteoglycans of peripheral and central stroma of the keratoconus cornea – Ultrastructure and 3D transmission electron tomography

Written by Nick Zhuang on 2019. Posted in Plant Science, PowerTome.

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UNI-EM: An Environment for Deep Neural Network-Based Automated Segmentation of Neuronal Electron Microscopic Images

Written by Nick Zhuang on 2019. Posted in ATUMtome, Neuroscience.

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Three-dimensional organization of transzonal projections and other cytoplasmic extensions in the mouse ovarian follicle

Written by Nick Zhuang on 2019. Posted in ATUMtome, Cell Biology.

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Toxicity and cytopathology mediated by Bacillus thuringiensis in the midgut of Anticarsia gemmatalis (Lepidoptera: Noctuidae)

Written by Nick Zhuang on 2019. Posted in Cell Biology, PowerTome.

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Mouse pancreatic ductal organoid culture as a relevant model to study exocrine pancreatic ion secretion

Written by Nick Zhuang on 2019. Posted in Biomedical Science, PowerTome.

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Evaluation of the Structure of Myodural Bridges in an Equine Model of Ehlers-Danlos Syndromes

Written by Nick Zhuang on 2019. Posted in Biomedical Science, PowerTome.

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Combined loss of LAP1B and LAP1C results in an early onset multisystemic nuclear envelopathy

Written by Nick Zhuang on 2019. Posted in Cell Biology, PowerTome.

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Well-defined poly(ether sulfone)-b-polylactide: synthesis and microphase separation behavior

Written by Nick Zhuang on 2019. Posted in Plastics and Polymers, PowerTome.

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Nuclear membrane protein Lem2 regulates nuclear size through membrane flow

Written by Nick Zhuang on 2019. Posted in Cell Biology, PowerTome.

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GLP-1 receptor agonist liraglutide has a neuroprotective effect on an aged rat model of Wolfram syndrome

Written by Nick Zhuang on 2019. Posted in Biomedical Science, MTXL.

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Brain activity regulates loose coupling between mitochondrial and cytosolic Ca2+ transients

Written by Nick Zhuang on 2019. Posted in ATUMtome, Cell Biology.

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Quantitative synchrotron X-ray tomography of the material-tissue interface in rat cortex implanted with neural probes

Written by Nick Zhuang on 2019. Posted in Neuroscience, PowerTome.

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Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS

Written by Nick Zhuang on 2019. Posted in Neuroscience, PowerTome.

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Chlamydia trachomatis CT229 Subverts Rab GTPase-Dependent CCV Trafficking Pathways to Promote Chlamydial Infection

Written by Nick Zhuang on 2019. Posted in Biomedical Science, MT7000.

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Large Volume Electron Microscopy and Neural Microcircuit Analysis

Written by Nick Zhuang on 2018. Posted in ATUMtome, Neuroscience.

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Correlated Light-Serial Scanning Electron Microscopy (CoLSSEM) for ultrastructural visualization of single neurons in vivo

Written by Nick Zhuang on 2018. Posted in ATUMtome, Neuroscience.

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Flexible Learning-Free Segmentation and Reconstruction of Neural Volumes

Written by Nick Zhuang on 2018. Posted in ATUMtome, Neuroscience.

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A micro-CT-based method for quantitative brain lesion characterization and electrode localization

Written by Nick Zhuang on 2018. Posted in ATUMtome, Neuroscience.

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Morphological evidence of telocytes in human synovium

Written by Nick Zhuang on 2018. Posted in Biomedical Science, MTX.

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Thrombospondin-1 protects against Aβ-induced mitochondrial fragmentation and dysfunction in hippocampal cells

Written by Nick Zhuang on 2018. Posted in Biomedical Science, MTXL.

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Basal and starvation-induced autophagy mediates parasite survival during intraerythrocytic stages of Plasmodium falciparum

Written by Nick Zhuang on 2018. Posted in Environmental Science and Sustainability, PowerTome.

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Biophotonic approach for the characterization of initial bitter-rot progression on apple specimens using optical coherence tomography assessments

Written by Nick Zhuang on 2018. Posted in MT7000, Plant Science.

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Altered secretion patterns and cell wall organization caused by loss of PodB function in the filamentous fungus Aspergillus nidulans

Written by Nick Zhuang on 2018. Posted in MT6000, Plant Science.

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Reappraising the microscopic anatomy of human testis: identification of telocyte networks in the peritubular and intertubular stromal space

Written by Nick Zhuang on 2018. Posted in Cell Biology, MTX.

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The programmed DNA elimination and formation of micronuclei in germ line cells of the natural hybridogenetic water frog Pelophylax esculentus

Written by Nick Zhuang on 2018. Posted in Environmental Science and Sustainability, PowerTome.

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Widespread bone-based fluorescence in chameleons

Written by Nick Zhuang on 2018. Posted in Environmental Science and Sustainability, MT7000.

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GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections

Written by Nick Zhuang on 2018. Posted in Cell Biology, MT6000.

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Microscopic mechanisms of deformation transfer in high dynamic range branched nanoparticle deformation sensors

Written by Nick Zhuang on 2018. Posted in MTX, Nanotechnology and Advanced Materials, Plastics and Polymers.

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De novo targeting to the cytoplasmic and luminal side of bacterial microcompartments

Written by Nick Zhuang on 2018. Posted in Cell Biology, MTXL.

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Tamoxifen therapy in a murine model of myotubular myopathy

Written by Nick Zhuang on 2018. Posted in Biomedical Science, MT6000.

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Informative three-dimensional survey of cell/tissue architectures in thick paraffin sections by simple low-vacuum scanning electron microscopy

Written by Nick Zhuang on 2018. Posted in ATUMtome, Cell Biology.

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Perpendicular orientation between dispersed rubber and polypropylene molecules in an oriented sheet

Written by Nick Zhuang on 2018. Posted in Minerals, Nanotechnology and Advanced Materials, PowerTome.

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TGNap1 is required for microtubule-dependent homeostasis of a subpopulation of the plant trans-Golgi network

Written by Nick Zhuang on 2018. Posted in Plant Science, PowerTome.

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Towards the scale-up of the formation of nanoparticles on α-Ag2WO4 with bactericidal properties by femtosecond laser irradiation

Written by Nick Zhuang on 2018. Posted in Advanced Materials, Nanotechnology and Advanced Materials, PowerTome.

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Tuning anhydrous proton conduction in single-ion polymers by crystalline ion channels

Written by Nick Zhuang on 2018. Posted in Nanotechnology and Advanced Materials, Plastics and Polymers, PowerTome.

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Partially oxidized polyvinyl alcohol conduit for peripheral nerve regeneration

Written by Nick Zhuang on 2018. Posted in Biomedical Science, PowerTome.

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Partially oxidized polyvinyl alcohol conduit for peripheral nerve regeneration

Written by Nick Zhuang on 2018. Posted in Biomedical Science, PowerTome.

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Mitochondria Bound to Lipid Droplets Have Unique Bioenergetics, Composition, and Dynamics that Support Lipid Droplet Expansion

Written by Nick Zhuang on 2018. Posted in Cell Biology, MTX.

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Plant Endocytosis Requires the ER Membrane-Anchored Proteins VAP27-1 and VAP27-3

Written by Nick Zhuang on 2018. Posted in Plant Science, PowerTome.

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Whole-brain serial-section electron microscopy in larval zebrafish

Written by Nick Zhuang on 2017. Posted in ATUMtome, Neuroscience.

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Localization of phosphorylated connexin 43 using serial section immunogold electron microscopy

Written by Nick Zhuang on 2017. Posted in ATUMtome, Cell Biology.

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Multi-walled carbon nanotubes act as a chemokine and recruit macrophages by activating the PLC/IP3/CRAC channel signaling pathway

Written by Nick Zhuang on 2017. Posted in Cell Biology, MTX.

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Irisin prevents and restores bone loss and muscle atrophy in hind-limb suspended mice

Written by Nick Zhuang on 2017. Posted in Biomedical Science, MTX.

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Muscle and adipose tissue morphology, insulin sensitivity and beta-cell function in diabetic and nondiabetic obese patients: effects of bariatric surgery

Written by Nick Zhuang on 2017. Posted in Biomedical Science, MTX.

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